(2R)-7-Azido-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2-methylheptanoic acid - Names and Identifiers
Name | (2R)-7-Azido-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2-methylheptanoic acid
|
Synonyms | (S)-N-FMoc-2-(5'-azido)alanine (S)-N-Fmoc-2-(5'-Azido)Alanine (R)-N-Fmoc-2-(5'-azido)alanine (R)-N-Fmoc-2-(5'-azidopentyl)alanine (2R)-7-Azido-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2-methylheptanoic acid (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-7-azido-2-methylheptanoic acid
|
CAS | 1191429-12-5
|
InChI | InChI=1S/C23H26N4O4/c1-23(21(28)29,13-7-2-8-14-25-27-24)26-22(30)31-15-20-18-11-5-3-9-16(18)17-10-4-6-12-19(17)20/h3-6,9-12,20H,2,7-8,13-15H2,1H3,(H,26,30)(H,28,29)/t23-/m1/s1 |
(2R)-7-Azido-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2-methylheptanoic acid - Physico-chemical Properties
(2R)-7-Azido-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2-methylheptanoic acid - Introduction
(S)-N-Fmoc-2-(5 '-azido) alanine is an organic compound. Its chemical formula is C26H20N4O4. The following is a detailed description of its nature, use, formulation and safety information:
Nature:
(S)-N-Fmoc-2-(5 '-azido) alanine is a solid with pale yellow crystals. It is an aromatic compound with good solubility and is soluble in common organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane (DCM). It is stable under normal laboratory conditions.
Use:
(S)-N-Fmoc-2-(5 '-azido) alanine is an important derivative in the field of organic synthesis. It is commonly used in peptide synthesis as part of a protecting group (protecting the amino group). In addition, it can also be used for the synthesis and research of compounds with biological activity.
Preparation Method:
(S)-N-Fmoc-2-(5 '-azido) alanine can be prepared by chemical synthesis. A common synthetic method is to react alanine and Fmoc-OSu (dimethyl sulfoxide N-O-azomethylacyl) to prepare an intermediate, and then introduce the azide group by Hydrazine (hydrazine) reaction.
Safety Information:
There is limited safety data on (S)-N-Fmoc-2-(5 '-azido) alanine, but in general, it is relatively safe to use under normal laboratory conditions. However, as an organic compound, laboratory safety procedures must be followed. Pay attention to avoid contact with eyes, skin and respiratory tract, avoid ingestion. Wear protective glasses, gloves and laboratory coats when working. In the event of any accident, rinse immediately with clean water and seek medical assistance.
Last Update:2024-04-10 22:29:15